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Discussion These on Helicobacter Pylori

Question 1

The first step in the treatment of this patient is Helicobacter pylori eradication considering that the serum test gave positive results. Therefore, I would prescribe appropriate antibiotics, for instance, amoxicillin, clarithromycin, and metronidazole (Testerman & Morris, 2014). Helicobacter pylori drug therapy is appropriate in preventing the proliferation of these bacteria. In case the patient remains symptomatic, I would also prescribe proton pump inhibitors (PPI) (Moayyedi et al., 2017). They help in acid suppression and prevent the proliferation of Helicobacter pylori bacteria. Some examples of PPIs that may be prescribed to the patient include omeprazole, lansoprazole, and rabeprazole.

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If the symptoms still fail to improve, I would prescribe tricyclic antidepressants, such as flupenthixol and melitracen. Prokinetics serve as the next course of treatment in case the patient does not respond to the previous therapy (Moayyedi et al., 2017). Metoclopramide, erythromycin, and domperidone comprise some prokinetics that may be prescribed to this particular person. In case these medications fail to cause the intended therapeutic result and alleviate the symptoms, clinicians may consider alternative and even complementary medicine therapies that may include herbal medicines.

Question 2

The duration of the Helicobacter pylori drug therapy ranges from seven to fourteen days. It often depends on the course of treatment or medications selected for the eradication of these bacteria. The subsequent acid suppression therapy that entails using PPIs or prokinetic agents lasts for about 4-8 weeks (Talley & Ford, 2015). The patient may require a drug holiday of about three months in case such treatment succeeds. However, if the use of PPIs fails to produce satisfactory outcomes, tricyclic antidepressant therapy is initiated. Its duration is approximately three months (Talley & Ford, 2015). After this, the patient will require a drug holiday of about three months, but only if the tricyclic antidepressant therapy achieves the intended treatment outcomes (Talley & Ford, 2015). As such, the duration of therapy varies depending on specific medications and the time required for causing therapeutic effects without exposing patients to safety concerns.

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Question 3

I would prescribe other medications to help in dealing with the side effects of the prescribed medications. For instance, I would use antidiarrheal medications, such as loperamide and Kaopectate, because these can assist in controlling diarrhea, which is a common side effect associated with Helicobacter pylori drug and PPI therapies. Also, patients taking the prescribed medications experience nausea and abdominal pain as side effects. With this in mind, they may require a drug that treats stomach pain, as well as an antiemetic for nausea. Therefore, Kaopectate can help in treating these side effects considering its pharmacological properties. The drug also assists with vomiting that may occur in the patient as a side effect of the antibiotics used as part of the Helicobacter pylori drug therapy.

Question 4

The treatment would vary in several ways in case the patient has gastroesophageal reflux disease (GERD). First, the eradication of Helicobacter pylori bacteria is not a primary treatment goal in GERD patients. As Buttaro, Trybulski, Polgar-Bailey, and Sandberg-Cook (2013) note, the testing and subsequent treatment of Helicobacter pylori is not a standard strategy when dealing with GERD patients in the United States. Also, the treatment of the latter does not require mandatory prescriptions of H2 receptor antagonists. GERD patients can get these medications over-the-counter and only take them when there is a high likelihood of experiencing a surge in gastric acid and reflux symptoms (Buttaro et al., 2013). They only receive PPIs for acid suppression and maintenance. Another variation is that GERD patients also require a shorter course of PPI therapy that is about two months (Buttaro et al., 2013). They may require promotility agents prescribed alongside acid suppression therapy to facilitate gastric emptying. A combination of these therapies helps in raising the pressure in the lower esophageal sphincter (LES) in GERD patients.

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